CMS Electronic Prescribing for Controlled Substances (EPCS) Program

Attention: Waiver Application Submission Period for MY 2024 Closing Tomorrow

The waiver application submission period for measurement year (MY) 2024 for the Centers for Medicare & Medicaid Services (CMS) Electronic Prescribing for Controlled Substances (EPCS) Program is closing Tomorrow, November 18, 2025, at 8 p.m. ET (5 p.m. PT).

Note that tomorrow is the last day prescribers or their designated representatives can submit a waiver application for a prescriber who’s considered non-compliant with the EPCS Program for MY 2024. CMS recommends that prescribers or their designated representatives log into the CMS EPCS Prescriber Portal to look up their MY 2024 compliance status to ensure that they have a compliant status or have submitted a waiver application for the measurement year.

By the end of December 2025, each prescriber and designated representative who submitted a waiver application:

• Must check for and respond to any waiver application reviewer comments addressed to them
• Will be notified whether the prescriber’s waiver application was approved or denied
• Will receive the prescriber’s final compliance status for the measurement year

For more on how to check a compliance status and submit a waiver application, review the CMS EPCS Program Waiver Application Fact Sheet and the CMS EPCS Prescriber Portal & Waiver Application User Guide.

MY 2024 Compliance Status

On the EPCS Prescriber Portal, prescribers can review their MY 2024 compliance status, as well as their other compliance information, which informs them whether they’re currently considered compliant or non-compliant with the program for MY 2024, and any associated waiver application process or review that may be available to non-compliant prescribers before CMS provides final compliance status determinations on the EPCS Prescriber Portal.

Again, prescribers or their designated representatives may submit a waiver application on the EPCS Prescriber Portal until tomorrow, November 18, 2025, at 8 p.m. ET (5 p.m. PT).

For more details on how CMS determines program compliance, visit the “Compliance Overview” section on the CMS EPCS Program webpage.

HARP User ID and Password

To log into the EPCS Prescriber Portal, prescribers and their designated representatives first need a Health Care Quality Information Systems (HCQIS) Access Roles and Profile (HARP) account user ID and password. If a user doesn’t have a HARP account, they can apply for one on the HARP Create an Account webpage.

For more information on what MY 2024 compliance information is available on the EPCS Prescriber Portal, visit the EPCS Program webpage.

CMS EPCS Program Support

CMS is committed to providing support and resources to prescribers included in the CMS EPCS Program.

• The CMS EPCS Program webpage is the centralized location for program resources and updates.
• Prescribers can sign up for the CMS EPCS Program Listserv for program updates and upcoming deadlines.
• The Center for Clinical Standards and Quality (CCSQ) Support Central is the primary point of contact for questions on the CMS EPCS Program.