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FDA dampens Replimune’s hopes for melanoma drug Read in browser
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28 July, 2026
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Cambrex Advances US and European Expansions
Cambrex continues to expand its facilities across the United States and Europe, including a $120 million investment in API manufacturing capabilities in Charles City, Iowa, and a $30 million investment in analytical development and process R&D in Milan, Italy.
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top stories
1. Alnylam's stock is down 30% despite a booming biotech market. Here's why.
2. FDA staff say Replimune's pivotal melanoma trial failed to prove RP1 works, pushing down stock
3. Updated: GSK reveals three-year blueprint to cut costs and propel R&D
4. Claris collects $118M to take eye drop into pivotal testing next year
5.
news briefing
Oak Hill Bio merges with RA Capital SPAC; InnoCare's TYK2 drug hits in Phase 3
6. Updated: Altimmune’s GLP-1-based shot cuts drinking in patients with alcoholism
7. Capricor shares plunge after FDA says DMD therapy lacks efficacy ahead of adcomm
more stories
 
Karen Weintraub
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Alnylam’s stock has lost 30% of its value this year, despite a successful drug launch and accurate sales predictions. Max Gelman unpacks the reasons behind this falloff and what the company is doing about it. 

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Karen Weintraub
Deputy Editor, Endpoints News
1
by Max Gelman

Al­ny­lam is one of bio­phar­ma’s biggest mys­ter­ies so far in 2026. The broad­er mar­ket is see­ing a resur­gence af­ter years of a bear­ish en­vi­ron­ment. M&A...

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2
by Max Bayer

FDA staff threw cold wa­ter on Replimune’s ad­vanced melanoma drug ahead of a crit­i­cal meet­ing with agency ad­vi­sors, writ­ing that the piv­otal study de­sign failed...

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Luke Miels, GSK CEO
3
by Ayisha Sharma

Just a lit­tle over six months in­to his tenure as CEO at GSK, Luke Miels is mak­ing his mark.

The UK phar­ma on Tues­day out­lined...

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4
by Kyle LaHucik

Claris Bio has a fresh CEO, new board chair and $118 mil­lion for two piv­otal tri­als to see if its eye drop can suc­ceed in a...

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