podcast
The ouster of CDC's director, and a look at VCs
What is happening to the leadership of the Centers for Disease Control and Prevention? Which biotech venture capital firm has generated the best returns for investors? And how did cat hair show up inside a major drug manufacturing plant?
We discuss all that on this week’s episode of the “The Readout LOUD,” STAT’s biotech podcast. We bring on Washington correspondent Chelsea Cirruzzo to explain the ouster of CDC Director Susan Monarez and the resignations of other top officials.
We also chat about STAT’s annual VC rankings report, as well as ongoing issues at a major drug manufacturing site that was owned by Catalent and now owned by Novo Nordisk.
Listen here.
alzheimer's
FDA orders earlier MRI scans for Leqembi
The Food and Drug Administration is tightening safety rules for Eisai and Biogen’s Alzheimer’s drug Leqembi, calling for an earlier MRI scan between the second and third infusions of the biologic. This comes after regulators identified six deaths linked to brain swelling, or amyloid-related imaging abnormalities with edema. Up until now, scans were only required before the fifth, seventh, and 14th doses.
The move brings Leqembi closer in line with Eli Lilly’s rival Kisunla, which already mandates earlier monitoring, as regulators aim to catch potentially fatal complications sooner.