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Why Your Morning Coffee Isn't Working (unless you are Marc Andreessen)

Most energy drinks just dump caffeine in your system to block adenosine. You feel alert for a bit, then your cortisol spikes and you crash. Not ideal.

Better move: pair caffeine with L-theanine. It promotes alpha-wave activity, which means you get the boost without feeling like you're vibrating. Matcha does this naturally: slower uptake, fewer jitters, steadier focus throughout the day.

Here's what actually helps:

  • Citicoline keeps your attention sharp
  • Bacopa helps with memory (takes a few weeks to kick in)
  • Lion's mane supports nerve growth (still early research, but promising)
  • Rhodiola and cordyceps help you handle stress without frying your nervous system

Add some turmeric and vitamin C to deal with oxidative stress. B-vitamins keep your cells running...

The best ready-made formulation I've found which achieves this and more is Magic Mind, it packs all of this into one shot (matcha, L-theanine, nootropics, adaptogens, the complete package). It's designed for mental performance without the crash or the pill fatigue.

​There's a 50% off your subscription here, or 20% off your one time purchase​

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Time Saved This Week: 11 hours, 35 minutes

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​NEW Premium Notes​

​Aristotle, Thiel Fellowship, and Human Greatness | Michael Gibson on Cost of Glory with Alex Petkas​

  • What do entrepreneurs and philosophers have in common? They both question the nature of reality and search for truths that can reshape the world. In fact, some of today's most notable entrepreneurs come from a philosophy background, including Peter Thiel, Reid Hoffman, and the guest featured on these Premium Podcast Notes, Michael Gibson. From his study of Aristotle, he explains how to evaluate human greatness, why there's no better feeling than pulling off the heist with your friends, why Aristotle was the OG Giga Chad, and how SaaS (Startups as a Self) can bring out your true potential

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​Essentials: Science of Building Strong Social Bonds with Family, Friends & Romantic Partners​

  • If you’ve ever wondered why some days you want people around and other days you just want to hide, Huberman gets into all of that in this episode. He talks about how the brain is basically wired to need a certain amount of social time and how that messes with us… loneliness, pulling back, reaching out, all of it. He also breaks down how things like oxytocin and dopamine shape us from when we’re little and play into whether we lean introvert or extrovert. And he gives some easy, real-life ideas on how simply doing things together can actually make our relationships feel closer

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​Antonio Bianco, M.D., Ph.D. — Thyroid Function and Hypothyroidism: How New Approaches Are Transforming Care | The Drive with Peter Attia (#373)​

  • Antonio Bianco explains how our bodies actually make and use thyroid hormones, why a lot of lab test results don’t match how people feel, and why it’s not as simple as just checking a TSH box. If you’ve ever wondered why thyroid treatment is so confusing or why some folks still feel lousy even when their numbers look normal, you’ll get plenty out of this

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Top Premium Takeaways Of The Week


​Aristotle, Thiel Fellowship, and Human Greatness | Michael Gibson on Cost of Glory with Alex Petkas​

​XXXX Is the Highest External Good; it is your reputation among the people who matter most to you (not the masses)

A Little Bit of Madness Is Good — “Is this person crazy or crazy awesome?”

  • ​IQ is not...​
  • ​Being smart does not mean...​

Aristotle, The Original Giga Chad?

  • Greatness of soul: Judging yourself worthy of things that you are xxxx of (best)​
    • Vanity of soul: Judging yourself worthy of things that you are not worthy of
    • Smallness of soul: Judging yourself not worthy of things that you are xxxx of (worst)​
  • Greatness of soul is basically the original “Giga Chad”
    • “Giga Chad” may seem arrogant, but it’s because he...​

In Startups, XXXX Is Better Than Happiness

  • “There is something so wonderful about a group of friends working towards some once-thought-impossible goal and pulling it off. It’s one of the greatest things in life… I think that’s why we like heist movies so much. They’re pursuing a bad end, but there’s something so beautiful about a group of friends bringing out the best in each other to accomplish something.” – Michael Gibson
  • This resembles Aristotle’s virtuous friendship, where relationships are grounded in mutual respect, unbreakable trust, and a common goal

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​Essentials: Science of Building Strong Social Bonds with Family, Friends & Romantic Partners​

“From the day we are born until the day we die, the quality of our social bonds dictates much of our quality of life.”​ - Huberman

Introverts and Extroverts Are Not Just About Liking People or Being Shy... it is about how much...​

  • If you are an introvert, a little social interaction gives you...​
  • If you are an extrovert, you get less...​

​XXXX Is a Huge Tool for Building Strong Social Bonds

To Build or Deepen Any Relationship: try focusing on both feeling what others feel (emotional empathy) and actually making an effort to understand how they...​

  • Emotional empathy is about syncing your body with someone else, through stories, music, or doing stuff together
  • ​Cognitive empathy is about...​

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​Antonio Bianco, M.D., Ph.D. — Thyroid Function and Hypothyroidism: How New Approaches Are Transforming Care | The Drive with Peter Attia (#373)​

Good Advice for Patients: get a doctor who actually knows thyroid physiology, not just...​

Hyperthyroidism Is Way Less Common Than Hypothyroid Issues, and most often caused by xxxx (an autoimmune problem)

  • Main symptoms: fast heart rate, feeling jittery, sweaty...​
  • Graves’ is diagnosed by high T4 and T3, low TSH, and positive antibodies
  • Treatment choices:
    • Medicines to block thyroid production
    • Surgery, which is more...​
    • Radioactive iodine, now less popular because of...​

Two FDA-Approved Meds for Thyroid Hormone Replacement Therapy: T4 (Synthroid, a bunch of generics/brands) and T3 (mainly for special cases)

Too Much Iodized Salt Can Trigger XXXX​

  • Interesting fact: Japan eats a lot of iodine (from seaweed) and has way more...​

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​Is Embryo Selection The Future of Reproduction? | Dr Jonathan Anomaly on Modern Wisdom with Chris Williamson​

Technology vs. Genetic Engineering Misconception: Embryo selection ≠ gene editing; no genome manipulation occurs

  • Reveals natural genetic variation within existing embryos; enables informed choice of which to implant
  • About 70% of Americans support disease screening; only 40% support intelligence screening, which reflects Western taboo around mental trait selection, despite similar genetic understanding as physical traits

Inequality & Societal Impact: Won’t create dramatic single-generation changes (modest IQ increases only)

  • Assortative mating already selects for intelligence—embryo selection extends the existing pattern
  • Individual choice vs. government mandate is a critical distinction; market access fears often outweigh technology fears themselves

Validation and Implementation Standards: Polygenic risk scores aggregate many gene effects into a single probability estimate

  • Examples: diabetes, heart disease, depression risk
  • Doctors are comfortable with monogenic disorders but hesitant about polygenic/neurorisk conditions, despite both being probabilistic

The Emergence of Ethical Paradoxes: “Wrongful life” lawsuits likely (child claims shouldn’t have been born due to preventable condition)

  • Identity question: Is reducing breast cancer risk by 46% actually replacing a person with a different individual?
  • Can one be pro-choice yet anti-embryo-selection? Pro-cancer-awareness yet anti-screening?

Regulatory Philosophy: Social norms > government regulation for trait boundaries (e.g., selecting against dark triad traits acceptable; selecting for them questionable)

  • Decentralization is preferred: individual adoption vs. centralized mandate
  • The “Blank slate” worldview is challenged by genetic technology reality

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​Matt Abrahams: How to Speak Clearly & With Confidence | Huberman Lab​

“I’m on a personal mission to stop presentations and meetings from starting with people just giving their credentials, telling the titles of what they’re saying. Get us hooked. I tell people it’s like an action movie. How does every action movie you’ve ever seen start? With action.” – Matt Abrahams

The Only Way You Get Better at Communication Is Through 3 Things: repetition, reflection, and feedback

  • You have to practice because nobody has ever thought their way to better communication
  • You have to reflect because doing the same thing over and over, expecting different results, is insanity, and that’s how many people communicate
  • You also have to have trusted others who can give you honest feedback

Record Yourself Speaking and Watch It 3 Times: once with sound only, once with video only, and once with both. You’ll notice things you missed before

To Avoid Blanking Out:

  • Avoid memorizing because memorizing invites blanking out. Have a clear structure, a road map, but you don’t know every word you’re going to say
  • Rationalize the fear. Ask yourself what the likelihood is that you’ll blank out in this upcoming communication. Most people say maybe 20%. Those are good odds
  • Ask yourself if it were to happen, what’s the worst thing that would happen? It would be incredibly embarrassing, awkward, and might have some short-term implications. But who in their life hasn’t been embarrassed, been in situations that are awkward?

If the Worst Happens and You Do Blank Out: Retrace your steps. Repeat what you just said. Most of us can remember what we just said, and that gets us back on track

  • If that doesn’t work, distract your audience by asking a question
    • When this happens to Matt, he says, “I want to pause for a moment and have you think about how what we’ve just discussed can be applied to your life.”

How to Ask for a Raise?

  • When you ask matters a lot: look at your boss’s schedule before you ask for a raise. Are you having the fifth meeting in a row before you go in? Maybe it’s better to go tomorrow when you’re early because context matters
  • When positioning yourself for a raise, approach it from their perspective and think about how you can position it so that you are demonstrating your value from their perspective