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30 September, 2026
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top stories
1. When is one trial enough? Drugmakers push FDA for greater clarity on draft guidance
2. FDA nominee Overton backs swifter trials, dodges calls to rebuke Trump if needed
3. PhRMA picks Eric Cantor as next chief
4. Ned Sharpless joins Hatteras, as Andrew Witty returns to the VC firm as chairman
5. White House takes stock of US-based manufacturing for 86 essential drugs
Zachary Brennan
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Heidi Overton dodged many tough questions in her confirmation hearing last week, potentially raising questions about her ability to stand up to HHS Secretary Robert F. Kennedy Jr. when it comes to controversial issues like vaccine scheduling and mifepristone. The Senate health committee said Monday that Overton's confirmation vote is on hold until after the midterm elections. Stay tuned for more.

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Zachary Brennan
Senior Editor, Endpoints News
@ZacharyBrennan
1
by Zachary Brennan

Phar­ma­ceu­ti­cal com­pa­nies and in­dus­try groups are call­ing on the FDA to pro­vide more de­tails and ex­am­ples about when spon­sors can re­ly on one piv­otal tri­al...

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FDA commissioner nominee Heidi Overton testifies in front of the Senate HELP Committee in Washington, DC on Tuesday, Sept. 24, 2026. (Tom Williams/AP Images)
2
by Max Bayer

Hei­di Over­ton’s con­fir­ma­tion hear­ing to lead the FDA as com­mis­sion­er con­clud­ed af­ter a tense but large­ly re­spect­ful two hours of grilling from Sen­ate HELP Com­mit­tee...

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Eric Cantor, new PhRMA CEO (Mattie Neretin/Sipa USA/Sipa via AP Images)
3
by Max Bayer

For­mer House Ma­jor­i­ty Leader Er­ic Can­tor has been cho­sen as PhRMA’s next pres­i­dent and CEO, the group said Tues­day. The an­nounce­ment came short­ly af­ter End­points...

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4
by Kyle LaHucik

Hat­teras Ven­ture Part­ners, a North Car­oli­na VC firm that has backed 100 life sci­ences star­tups, an­nounced Wednes­day that it has at­tract­ed for­mer Na­tion­al Can­cer...

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5
by Zachary Brennan

The White House­'s Of­fice of Man­age­ment and Bud­get (OMB) is ask­ing for more in­for­ma­tion on the do­mes­tic pro­duc­tion of 86 es­sen­tial med­i­cines, such as the...

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