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7 October, 2026
$142 billion in 340B medicine markups
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The Patent Clock Is Al­ready Run­ning. Why De­vel­op­ment Speed Is Al­so a Com­mer­cial Strat­e­gy
spotlight
top stories
1. Vaccine for deadly brain cancer narrowly misses goal in key trial
2. TCGX doubles down on China with $600M Asia-focused fund
3. Updated: CAR-T biotech Caribou to pull the plug after struggling to find funding
4. Novartis-partnered biotech nabs $150M Series B to move into the clinic
5. Bexorg gets $28M ARPA-H award to run longer tests on ‘rebooted’ human brains
6.
news briefing
Nuvig drops a Phase 2 trial; Cerevance reports Parkinson's progress
7. In DC, a secretive new thorn has appeared in the pharma industry's side
8. AstraZeneca heralds new R&D facility in that ‘other’ Cambridge
more stories
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Karen Weintraub
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We’re featuring a couple of failures today: MimiVax’s glioblastoma drug didn't quite meet statistical significance in a Phase 2b trial, and once-high-flying Caribou is seemingly headed for closure, as Lei Lei Wu and Ayisha Sharma explain. But there’s still plenty of money flowing into biotech, as demonstrated by VC firm TCGX and Novartis-partnered Matchpoint Therapeutics. Kyle LaHucik and Max Gelman have the details.

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Karen Weintraub
Deputy Editor, Endpoints News
1
by Lei Lei Wu

A brain can­cer ef­fort more than a decade in the mak­ing has cul­mi­nat­ed in a dis­ap­point­ing study re­sult — but re­searchers be­hind it are con­tend­ing...

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2
by Kyle LaHucik

Chen Yu's TCGX, a pri­vate and pub­lic biotech in­vest­ment firm, is go­ing to in­vest di­rect­ly in life sci­ences com­pa­nies in Chi­na and else­where in Asia...

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3
by Ayisha Sharma

Cari­bou Bio­sciences is reach­ing the end of the road.

The Cal­i­for­nia biotech said Tues­day it is shelv­ing two al­lo­gene­ic CAR-T cell ther­a­py pro­grams and seek­ing...

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4
by Max Gelman

Match­point Ther­a­peu­tics, a biotech part­nered with No­var­tis, has put to­geth­er its lat­est fi­nanc­ing round.

The $150 mil­lion Se­ries B will help fundMatch­point’s ef­forts to...

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5
by Ryan Cross

For years, sci­en­tists as­sumed that cells in the brain be­gan de­cay­ing im­me­di­ate­ly af­ter death. But re­searchers threw ice on that the­o­ry sev­en years ago when...

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News Briefing: Quick hits from the biopharma web